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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO2
All Species:
6.36
Human Site:
S162
Identified Species:
17.5
UniProt:
Q56NI9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56NI9
NP_001017420.1
601
68307
S162
I
K
P
V
S
R
N
S
R
N
S
K
Q
N
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543224
598
67974
S165
I
K
P
Q
S
K
N
S
K
S
S
K
Q
N
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIB9
592
67255
K172
K
S
K
S
R
N
L
K
N
S
K
P
N
Q
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508920
682
76075
A211
Q
I
G
A
A
F
F
A
T
R
K
K
A
H
P
Chicken
Gallus gallus
XP_420012
679
73766
V219
L
K
K
V
K
A
D
V
P
P
K
K
P
S
V
Frog
Xenopus laevis
NP_001089603
640
69941
S175
P
Q
S
D
K
P
T
S
K
K
G
T
E
I
N
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
S168
Q
T
D
Q
V
L
K
S
T
M
A
P
I
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
N229
S
E
R
S
P
G
G
N
V
E
G
K
K
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146746
323
35496
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
74.2
N.A.
69
N.A.
N.A.
45.8
37.4
36.7
37.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
84.1
N.A.
80
N.A.
N.A.
60.4
53.4
51.5
53.5
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
0
N.A.
N.A.
6.6
20
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
6.6
N.A.
N.A.
26.6
40
26.6
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
21.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
12
0
12
0
0
12
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
12
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
0
0
0
0
0
12
0
0
12
0
0
% E
% Phe:
0
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
12
0
0
12
12
0
0
0
23
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% H
% Ile:
23
12
0
0
0
0
0
0
0
0
0
0
12
12
0
% I
% Lys:
12
34
23
0
23
12
12
12
23
12
34
56
12
0
0
% K
% Leu:
12
0
0
0
0
12
12
0
0
0
0
0
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
12
23
12
12
12
0
0
12
23
12
% N
% Pro:
12
0
23
0
12
12
0
0
12
12
0
23
12
0
12
% P
% Gln:
23
12
0
23
0
0
0
0
0
0
0
0
23
12
0
% Q
% Arg:
0
0
12
0
12
12
0
0
12
12
0
0
0
0
23
% R
% Ser:
12
12
12
23
23
0
0
45
0
23
23
0
0
23
0
% S
% Thr:
0
12
0
0
0
0
12
0
23
0
0
12
0
12
0
% T
% Val:
0
0
0
23
12
0
0
12
12
0
0
0
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _